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Two pitching options stand out to me as pretty strong plays. The first is David Price ($10,700) vs the Rockies in Boston. The Rockies have the 5th highest K% vs LHP at 25% and a mediocre wRC+ of 92. Rockies teams also tend to struggle on the road more so than regular teams because of the difference in park effects with how the ball moves in Coors vs a more neutral environment. Price opposes Jorge de la Rosa, a below average pitcher, so run support looks good. Price has a 5.5 ERA, but he's missing a ton of bats, has a very strong FIP, and it's reasonable to expect him to settle in eventually. His high ERA may drive his ownership rate down.
The second is Jeff Samardzija at home vs the Padres. The Padres have the 4th highest K% vs RHP at 25% and the worst wRC+ at 68. Samardzija is running a 2.66 ERA, 2.78 FIP and 22% K% and has pitched 7 or more innings in 6/9 starts. Samardzija is a good bet to pitch well, get some strikeouts, pitch deep into the game and be in position to get the win.
For hitters, a good lefty masher matchup takes place in Boston, where the below average Jorge de la Rosa brings his 10+ ERA to Fenway. Among qualified hitters since the start of 2015, Chris Young ($2,500) has hit LHP to a 167 wRC+ (9th best) with a .249 ISO. He has been one of the best lefty mashers in the game in that time, and he's priced affordably.
Manny Machado ($3,700) has made significant improvements in his game this year and is hitting RHP to a 167 wRC+. He is listed as a shortstop, which provides huge value over the normal shortstop. MLB average wRC+ for a SS is about 85, which means Machado has been about 82% more productive offensively than the average MLB SS. He faces Doug Fister, a below average RHP.
In Washington, Matt Harvey faces the Nationals. Harvey looks nothing like his former ace self, and has been getting destroyed by lefties this year to a .353/.425/.576 slash. He has also given up the second most line drive launch angles by a pitcher all season. Daniel Murphy ($3,900) is hitting RHP to a 184 wRC+ and .242 ISO after making a mechanical adjustment late last season.
At catcher, Victor Martinez ($3,400) appears to be healthy. He's hit RHP to a 163 wRC+ and .212 ISO, and faces Jeremy Hellickson, a below average pitcher. Like Machado, playing Martinez at C gives a large advantage at the position, because catcher wRC+ is about 85 on average.