Reminder: Always double check the lineup card before rosters lock to make sure that a player you've chosen to roster is playing that day, and check the weather to make sure your players won't get rained out of their game.
FanDuel has made some tweaks to their scoring criteria for 2016. Check that out here. FanDuel is also only available to play for money in specific states. See their website for more details to see if FanDuel is playable for cash in your home state.
The pitcher I like most for tonight considering price and production is Aaron Nola ($8,400). Nola's 28% strikeout rate is 13th best in baseball, sandwiched between Madison Bumgarner and Chris Archer, and his 2.33 FIP is 6th best. He's thrown 7 innings in 5 out of 7 starts this year, and only gone below 6 IP once. His strong results are on the back of good command and one of the nastier curveballs in the game, which is an outstanding put away pitch with 2 strikes. He's racked up a 47% strikeout rate on his curve. I made these .gifs of Nola's curve in March:
Nola faces the Reds, who have the 10th highest K% vs RHP at 22.1% and the 4th lowest wRC+ at 80. The Reds have a poor overall team, so Nola's chances of getting the win aren't bad.
Since Nola isn't overly expensive, more flexibility to invest in hitting is available. The Mets are in Coors this weekend to face Eddie Butler. The Mets most productive hitters vs RHP this year have been Michael Conforto ($4,000, 170 wRC+), Yoenis Cespedes ($5,000, 148 wRC+) and Lucas Duda ($3,800, 132 wRC+). Cespedes in particular seems to feast on average to below average pitching just from watching him every day and had a 3 home run game in Colorado last year. Leadoff hitter Curtis Granderson ($3,700) has gotten off to a slow start, but as a leadoff hitter, he stands a good chance to get an extra crack at an extra PA vs someone who bats lower in the order and has the power to hit one out of the yard.
Another matchup that appears to be favorable for run scoring is in very hitter friendly Chase Field, where two below average pitchers oppose each other. Jake Peavy's peripherals indicate his 8+ ERA is going to come down, but his 5.13 FIP is still significantly below average. Patrick Corbin has seen a large dip in strikeouts, down to 15% this year from 22% last year, and it's led to a 4.12 ERA and 5.09 FIP. Buster Posey is affordable at $3,400 and he's hit LHP to a 142 wRC+ and .184 ISO since the start of last year, including a 147 wRC+/.189 ISO this year.