Eli Manning, NYG at WAS - Eli has a good matchup against division rivals, the Redskins. They surrender 248.3 passing yards per game and have allowed 20 passing touchdowns, including two or more passing touchdowns in each of the last five games. Needless to say, they are vulnerable against the pass. As in most season, Manning has been streaky this year. However, in two of his last three games he has thrown for 350 or more yards. He has 10 touchdowns in that span. In Week 3, he faced the Redskins and threw for 279 yards and two touchdowns. I would suggest that you keep an eye on the weather as the forecast expects it to rain heavily on Sunday in Washington.
Matthew Stafford, DET vs. PHI
Brian Hoyer, HOU vs. NO
Marcus Mariota, TEN vs. OAK
Blake Bortles, JAC vs. SD
Sleeper Alert: Josh McCown, CLE vs. BAL
Tyrod Taylor, BUF at KC- Taylor has not played well since returning from injury. He struggled last week against the Patriots and then hurt his shoulder towards the end of the game. He's expected to play this week, but has a tough matchup ahead of him. At the start of the season, the Chiefs were a defense that you wanted to start your quarterbacks against, but that's no longer the case. They have not allowed a multiple passing touchdown game to a quarterback in five consecutive games and no quarterback has thrown for over 252 yards in the last six games against them. The Chiefs have 12 interceptions in the last five games. On the road in a hostile environment, playing poorly as of late, and possibly not 100 percent healthy, these are all reasons that make Taylor an unappealing option this week.
Brock Osweiller, DEN vs. NE
Ryan Fitzpatrick, NYJ vs. MIA
Andy Dalton, CIN vs. STL
Ryan Tannehill, MIA at NYJ
Bust Alert: Matt Ryan, ATL vs. MIN
T.J. Yeldon, JAC vs. SD - Yeldon has a great matchup against the league's worst run defense. Opposing running backs are averaging 116 rushing yards, 5.1 rushing yards per carry, 5.4 receptions, 57.3 receiving yards per game, and have scored 13 touchdowns against the Chargers defense. They're also averaging over 22 fantasy points per game. Yeldon is averaging 19.3 touches per game and four targets per game. He's the Jaguars every down back. The one thing he lacks is touchdowns, but those are not difficult to come by when you play against the Chargers.
Javorius "Buck" Allen, BAL at CLE
Jonathan Stewart, CAR at DAL
Mark Ingram, NO at HOU
Doug Martin, TB at IND
Sleeper alert: Chris Ivory, NYJ vs. MIA
DeAngelo Williams, PIT at SEA - It's not easy benching Williams because not many running backs are getting the volume he receives. In games that he has started this season, Williams is averaging 21.3 carries per game. The thing is that this is not an ideal matchup. The Seahawks are surrendering 76.6 rushing yards per game, 3.61 rushing yards per carry, and have surrendered just three rushing touchdowns this season to opposing backs. They're also allowing the second fewest fantasy points per game. Williams has done well in Le'Veon Bell's absence, but he will be facing the second toughest run defense in the league.
Jeremy Hill, CIN vs. STL
Frank Gore, IND vs. TB
Latavius Murray, OAK at TEN
C.J. Anderson, DEN vs. NE
Bust Alert: Lamar Miller, MIA at NYJ
Golden Tate, DET vs. PHI - Tate is averaging 8.3 targets per game and has scored double-digit fantasy points in five of his last six games in PPR formats. He has seen three red zone targets in the last three games and has caught six or more passes in four of his last six games. The Eagles are allowing the second most fantasy points per game to receivers. They're surrendering 191.6 receiving yards and 15.1 receptions per game, while yielding 15 touchdowns to receivers. They've allowed seven touchdowns in their last three games, including two three touchdown games from opposing receivers. With Eric Ebron struggling to catch passes, Matthew Stafford could start looking in Tate's direction more often.
Stevie Johnson, SD at JAC
Brandin Cooks, NO at HOU
Stefon Diggs, MIN vs. ATL
Martavis Bryant, PIT at SEA
Sleeper Alert: Vincent Jackson, TB at IND
Sammy Watkins, BUF at KC - The Chiefs are surrendering the most fantasy points per game to receivers, but in their last five games, they've surrendered just three receiving touchdowns. Watkins is averaging 5.3 targets per game, but since returning from injury he's averaging seven targets per game. The issue is his efficiency. In the last two games, he has caught just 46 percent of the passes thrown his way. If he was getting a much higher amount of targets, I'd be able to live with that 46 percent. However, it's tough to deal with that low of a catch rate from someone who doesn't receive double-digit targets on a weekly basis. The Chiefs secondary has played much better as of late and Watkins will see plenty of Sean Smith on Sunday.
Anquan Boldin, SF vs. ARI
Brandon LaFell, NE at DEN
DeSean Jackson, WAS vs. NYG
Donte Moncrief, IND vs. TB
Bust Alert: Dez Bryant, DAL vs. CAR
Jordan Reed, WAS vs. NYG
Delanie Walker, TEN vs. OAK
Gary Barnidge, CLE vs. BAL
Charles Clay, BUF at KC
Vernon Davis, DEN vs. NE
Eric Ebron, DET vs. PHI
Kansas City Chiefs vs. Buffalo Bills
Arizona Cardinals at San Francisco