There are clear starts at QB this week based on match-ups. Peyton Manning of the Colts, Matt Ryan of the Falcons and Phillip Rivers of the Chargers stand out, but what do you do if you have the opportunity to start Shaun Hill of San Francisco or Derek Anderson of Cleveland or Trent Edwards of Buffalo?
If your #1 is Aaron Rodgers against good Carolina Panthers pass defense or David Garrard against a poor Houston Texans one or Brett Favre against a putrid Broncos' rush defense? Then the decision gets tricky. With fantasy play-offs on the line, sitting a QB with a favorable match-up for the more "established" QB could mean the difference between the play-offs and kick starting fantasy baseball preparations.
Ten Worst Pass Defenses: