Bengals: Is Carson Palmer fully recovered from his knee surgery?
Chiefs: Will Larry Johnson be affected by the change in coaches? Trent Green?
Is Tony Gonzalez still an elite TE or did his slippage in drafts portend something?
Saints: Does Reggie Bush live-up to the hype? What about former Top 10 pick Deuce McAllister? Can Drew Brees produce with a no-marquee cast of receivers as he did in SD? Will he be able to make one of them marquee a la TE Antonio Gates?
Browns: Is Braylon Edwards a top WR? Will QB Charlie Frye improve? Is Kellen Winslow as good as he thinks he is?
Eagles: Does WR Dante Stallworth finally live-up to his 2004, 2005 and 2006 sleeper label? Who punches the ball in from inside the five?
Texans: Will Andre Johnson finally breakout? Can Gary Kubiak transplant the running system from Denver to Houston to make the Reggie Bush non-selection moot? Will Mario Williams do the same?
Seahawks: How is Darrel Jackson's knee? Does Shaun Alexander miss Steve Hutchinson? Nate Burleson - the latest in sleeper failure?
Lions: Will new offensive coordinator Mike Martz make a difference? Is Jon Kitna the sleeper QB many have predicted?
Bears: Can QB Rex Grossman stave-off the onset of the Brian Greise Era?
Packers: Will Greg Jennings live-up to the universal hype as a potential #1? Can Ahman Green make it through the game without being listed as "doubtful" for Week Two?
Dallas: Will the Defense dominate? Can Julius Jones be better than a 3rd tier RB? T.O?
Jaguars: Will anyone step-up in their receiving core? Will Fred Taylor get to punch the ball in at the goal line?
49ers: Can Frank Gore get 100 yards against the Cardinals defense? Will Alex Smith be able to double or triple his career TD output in this game?
Cardinals: Has the O-line improved enough to let Edgerrin James earn his high-pick status? Does the Matt Leinart Era begin this week?