Reminder: Always double check the lineup card before rosters lock to make sure that a player you've chosen to roster is playing that day, and check the weather to make sure your players won't get rained out of their game.
Pitching
P is loaded today. Here are my thoughts on some:
Felix Hernandez faces the high strikeout Astros. They have a 25.4% K% vs RHP, second highest in baseball, but they've also been a top 10 offense vs RHP with a 99 wRC+ (9th best) and .179 ISO (3rd best). Since FanDuel weighs strikeouts so heavily in P scoring, Felix is my favorite choice. He gets a favorable matchup with Brett Oberholtzer going for Houston, too.
Clayton Kershaw faces the Padres in PetCo. First, a few words about the park: PetCo isn't the pitcher haven that it has historically been, likely because new construction changed the wind patterns. The grass was also a mess last week; a Rolling Stones concert tore the field up and balls on the ground were flying through the grass. This played a role to some degree in Andrew Cashner and Noah Syndergaard's crazy high BABIP games. It's not clear how the grass will play today, but keep in mind the condition it was in last week. As for the matchup, the Padres have the 7th highest K% vs LHP at 22.6% and 15th wRC+ at 98. Wil Myers just returned to the starting lineup yesterday, but he may need some adjustment time as he returns to timing up big league pitching coming off a wrist injury.
David Price faces the Indians, but they have the 2nd lowest K% vs LHP at 15.6% and 6th best wRC+ vs LHP at 110. It's not the ideal matchup.
Michael Pineda was skipped last time out in an effort to limit his innings and has not pitched in 11 days. It's fair to question what his command will look like after such a long layoff and disruption in routine.
Hitting
Dodgers LHB vs Odrisamer Despaigne
Despaigne has an ugly 4.83 career FIP vs LHB. Andre Ethier ($2,900) and Yasmani Grandal ($3,000) are both affordable and have excellent career+2015 numbers vs RHP.
Kyle Kendrick start
I am reluctant to list this as a pick because Miami's hitters aren't particularly impressive vs RHP (even the very expensive Giancarlo "only" has a 129 wRC+ vs RHP this year and 144 wRC+ dating back to the start of last), but Kendrick has a miserable 5.95 FIP this year, and it's a brutal 5.33 FIP away from Coors Field. Terrible run prevention will make mediocre hitting play up to good and good hitting play up to excellent. LHB Christian Yelich ($2,500) might be a decent punt-ish play; he was recently moved to 3rd in the order in front of Giancarlo Stanton, and while he's had a very poor line this year battling through injuries, he's just 2 months removed from being considered one of the brightest young outfielders in the game.
Punt plays
Here are some decent punt options that you can use to fit a King Felix into your lineup:
Rickie Weeks vs Brett Oberholtzer, $2,200
Weeks has a 133 wRC+ and .223 ISO vs LHP in 203 PA since the start of 2014. Oberholtzer is an average to below average pitcher vs RHB.
Billy Butler vs Hector Santiago, $2,200
Butler has a 137 wRC+ in 212 PA vs LHP since the start of 2014. Santiago has a significantly below average FIP of 4.76 in 141 IP vs RHB since the start of 2014.
Pablo Sandoval vs Drew Hutchison, $2,200
Sandoval's price has tanked because of poor performances vs LHP but he's hit RHP to a 130 wRC+ this year.
John Mayberry Jr. vs Alex Wood, $2,400
Mayberry is a career 126 wRC+ hitter vs LHP and is hitting them hard this year (23% of his at bats are ending in a hard hit ball vs LHP, significantly above average).
Follow me on Twitter at @TimFinn521, I usually tweet out more good options as lineups are released.